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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIN28B All Species: 31.52
Human Site: T86 Identified Species: 57.78
UniProt: Q6ZN17 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZN17 NP_001004317.1 250 27084 T86 E G E P V E F T F K K S S K G
Chimpanzee Pan troglodytes XP_001143220 250 27053 T86 E G E P V E F T F K K S S K G
Rhesus Macaque Macaca mulatta XP_001086990 248 26863 T86 E G E P V E F T F K K S S K G
Dog Lupus familis XP_539064 251 27158 T85 E G E P V E F T F K K S S K G
Cat Felis silvestris
Mouse Mus musculus Q45KJ6 247 26884 T84 E G E P V E F T F K K S P K G
Rat Rattus norvegicus P62961 322 35711 D110 D G E T V E F D V V E G E K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506004 274 29355 T106 E G E P L E F T F K K S S K G
Chicken Gallus gallus Q45KJ4 250 27379 T86 E G E P V E F T Y K K S S K G
Frog Xenopus laevis Q8AVK2 252 27965 T89 E G E P V E F T F K K S S K G
Zebra Danio Brachydanio rerio Q803L0 202 21867 N42 S G V C K W F N V R M G F G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRN5 195 21575 G36 A S P T E E C G C V R L G K C
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492281 196 21765 F37 N V S K G Y G F V I D D I T G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38896 201 19059 V42 D G G D D L F V H Q S S I R S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98 88.4 N.A. 85.5 24.5 N.A. 73.3 82.8 77.3 52.7 N.A. 31.6 N.A. 27.2 N.A.
Protein Similarity: 100 99.5 98 91.6 N.A. 90 36.9 N.A. 78.4 88.4 85.7 62.7 N.A. 44.4 N.A. 39.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 46.6 N.A. 93.3 93.3 100 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 60 N.A. 100 100 100 20 N.A. 20 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 33.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 8 % C
% Asp: 16 0 0 8 8 0 0 8 0 0 8 8 0 0 0 % D
% Glu: 62 0 70 0 8 77 0 0 0 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 85 8 54 0 0 0 8 0 8 % F
% Gly: 0 85 8 0 8 0 8 8 0 0 0 16 8 8 77 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 16 0 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 62 62 0 0 77 0 % K
% Leu: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 62 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % R
% Ser: 8 8 8 0 0 0 0 0 0 0 8 70 54 0 8 % S
% Thr: 0 0 0 16 0 0 0 62 0 0 0 0 0 8 0 % T
% Val: 0 8 8 0 62 0 0 8 24 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _